JURNAL KESEHATAN KARTIKA

DETERMINANT FACTORS OF HYPERTENSION IN HOUSEWIVES IN CIAMIS REGENCY

Sun, 31 Aug 2025 00:00:00 +0700

blood pressure rises above the defined normal range. Although hypertension is commonly experienced by the elderly, it can also affect adults, including housewives. Several risk factors for hypertension among housewives include age, menopausal status, use of contraceptives, dietary patterns, nutritional status, physical activity, and others. The aim of this study is to analyze the determinant factors of hypertension among housewives. Method: The cross-sectional study approach was used in the research design. The location of Ciamis Regency was chosen because it has the highest cases of hypertension in West Java based on the Kemenkes in 2018. Proportionate stratified sampling was the method employed for sampling with a total of 81 subjects in this study. Chi-square test was employed as the bivariate analysis. Result: The results show that there is a relationship between the variables nutritional status BMI (p-value = 0.016), abdominal circumference (p-value = 0.014), fat intake (p-value = 0.000), sodium intake (p-value = 0.006), and physical activity (p-value = 0.040). Conclusion: The incidence of hypertension in housewives is correlated with BMI, nutritional status, belly circumference, fat and sodium intake, and physical activity

PENERAPAN TERAPI MUSIK KLASIK PADA PASIEN SKIZOFRENIA DENGAN HALUSINASI PENDENGARAN DALAM MENURUNKAN TANDA DAN GEJALA HALUSINASI DI PRIMA HARAPAN BANDUNG

Ivena Nurmarisa, Fifi Siti Fauziah Yani — Fri, 05 Sep 2025 00:00:00 +0700

Background: Schizophrenia is a severe and persistent neurobiological brain disease. One of the symptoms of schizophrenia is hallucinations. Hallucinations are sensory perception disorders that occur in the absence of a real stimulus from the five senses, and it is often difficult to distinguish between reality and the unreal. Schizophrenia sufferers with auditory hallucinations need good treatment to control themselves from the impacts that will occur. Music therapy is a therapy that is often done because it is very easily accepted by the hearing. Music can affect imagination, intelligence, and memory, and can affect the pituitary in the brain to release endorphins. Music that produces alkaline effects is typically soft classical music, which makes it relaxing and calming. Objective: to provide nursing care by applying classical music therapy to schizophrenia patients with auditory hallucinations. Method: The method used is a descriptive method with a case study approach while the data collection process is through interviews and observations. Results: The results obtained after being given classical music therapy for 3 days which was done once a day for 15 minutes showed a decrease in signs and symptoms of hallucinations from 55% to 0%. Conclusion: The application of classical music therapy is effective in reducing the signs and symptoms of auditory hallucinations.

KADAR UREUM DAN KREATININ PADA ANAK SEKOLAH DASAR DI DEKAT PERTAMBANGAN EMAS SKALA KECIL DESA RANGAN TATE KABUPATEN GUNUNG MAS

Selviana Putri, Nazwa Arfah Safitri, Dwi Purbayanti — Sun, 31 Aug 2025 00:00:00 +0700

Background: Children living near artisanal and small-scale gold mining (ASGM) areas are at risk of exposure to hazardous chemicals, particularly mercury, which is known to be nephrotoxic. This study aimed to describe urea and creatinine levels as indicators of kidney function in children residing in ASGM areas. Method: The study employed a descriptive-analytic design with a cross-sectional approach. The sample consisted of 49 students from grades IV–VI of Rangan Tate Public Elementary School, selected using a total sampling technique. Data were collected through questionnaires, urea measurement using the Berthelot method, and creatinine measurement using the kinetic Jaffe method. Both methods are simple, fast, and inexpensive, although they require automated instruments for better precision. Data were analyzed descriptively and with Spearman correlation tests using SPSS version 30 (p<0.05). Result: The results showed that all respondents’ urea levels were within the normal range (11–39 mg/dL) with a mean of 28.3 mg/dL. In contrast, 69.4% of respondents had creatinine levels above the reference range (0.3–0.7 mg/dL), with a mean of 0.79 mg/dL. A significant correlation was found between children’s involvement in mining activities and creatinine levels (r=0.406; p=0.004), while no significant associations were observed between other variables and either urea or creatinine levels. A total of 8% of children were reported to participate in gold mining activities, and 20.4% lived within a radius of less than 1 km from mining sites. Conclusion: The increase in creatinine levels among most children living near ASGM areas indicates a potential risk of impaired kidney function. Further monitoring using more sensitive and accurate biomarkers is recommended for early detection of nephrotoxic effects.

HUBUNGAN PENGETAHUAN DENGAN PERILAKU PENCEGAHAN HIPERGLIKEMIA PADA PASIEN DIABETES MELITUS TIPE 2

iyar siswandi, Ikshan Ikshan — Fri, 05 Sep 2025 00:00:00 +0700

Background: Diabetes Mellitus is one of the endocrine system disorders that frequently occurs in society, with an annual increase of 56% in sufferers due to the instability of carbohydrates, fats, and proteins, leading to elevated blood glucose levels. This occurrence is influenced by the community's level of knowledge, which is lacking in understanding diabetes mellitus prevention methods. Objective : The purpose of this study is to determine the relationship between knowledge and the prevention of blood glucose levels in patients with type 2 diabetes mellitus. The sample used in this study consists of 55 respondents. This method utilizes a Cross-Sectional approach. Bivariate data analysis resulted in findings using the Chi-square test. Regarding the independent and dependent variables, a P-Value of 0.016 (<0.05) was obtained. Result of the OR = 0.241. Suggestions for future researchers can include prevention measures that may influence the increase in blood glucose levels. In conclusion, there is a significant relationship between knowledge and the prevention Hyperglycemia in type 2 diabetes mellitus patients

HUBUNGAN FUNGSI KOGNITIF TERHADAP ACTIVITY OF DAILY LIVING (ADL) PADA PASIEN PASCA STROKE

Anjelly Corolla, Bayu Saputra, T. Abdur Rasyid — Fri, 05 Sep 2025 00:00:00 +0700

Background: Post-stroke patients often experience cognitive impairment that can affect their ability to perform activities of daily living (ADL). Cognitive function plays an important role in supporting patients' independence in their daily lives. Impairment of this function can affect patients' ability to plan, remember, solve problems, and make decisions, thereby increasing their dependence on others and reducing their quality of life. Therefore, early identification and intervention of post-stroke cognitive impairment are essential to maximize recovery and improve patient independence. Objective : This study aims to analyze the relationship between cognitive function and ADL ability in post-stroke patients. Method : This study is a quantitative study with a cross-sectional design. This study was conducted using non-probability sampling with consecutive sampling. The sample in this study consisted of 30 respondents. The analysis used was univariate analysis with central tendency and frequency distribution as well as bivariate analysis using the person chi-square test. Result : The results of the analysis showed that the majority of respondents who had suffered a stroke were 58.97 years old, 17 respondents (56.7%) were male, 16 respondents (53.3%) had a high school education or equivalent, 22 respondents (72.2%) had ischemic stroke, 19 respondents (63.3%) had severe cognitive impairment, and 11 respondents (36.7%) had mild ADL dependence. The results of bivariate analysis using the Person Chi-Square test obtained a p-value of 0.098 (<0.05). conclusion : The results of this study can be concluded that there is no significant relationship between cognitive function and Activities of Daily Living (ADL) in post-stroke patients. Further research is recommended to explore the relationship between the level of cognitive impairment and ADL ability in post-stroke patients, as well as to identify factors that influence cognitive function recovery

DUKUNGAN KELUARGA DAPAT MENURUNKAN KECEMASAN PADA PASIEN PRE OPERASI MAYOR

Nur Fitri Apriliani, Achmad Setya Roswendi, Yuswandi Yuswandi — Fri, 05 Sep 2025 00:00:00 +0700

Background: Surgery is an action that is seen as a frightening experience for patients. Surgery requires patients to adapt, but the adaptability of each patient is different, triggering anxiety. Therefore, support from the family is needed to reduce preoperative anxiety. Objective : This study aims to determine the relationship between family support and anxiety in major preoperative patients in the Dustira Hospital surgical room. Method : The type of research used is correlation with a Cross Sectional approach. The population in this study were patients who would undergo major surgery, while the sample amounted to 67 respondents with purposive sampling. Data were taken directly using a questionnaire and then analyzed with univariate to see the frequency distribution and bivariate to see the relationship between variables. Result : The results of data analysis showed that respondents at Dustira Hospital had high family support (94%) and experienced severe preoperative anxiety (89.6%). There is a strong relationship between family support and anxiety in major preoperative patients in the Dustira Hospital surgical room with a p value = 0.000 ≤ α 0.05. Conclusion: There is a significant relationship between family support and preoperative anxiety in patients undergoing major surgery. The negative correlation indicates an inverse relationship: the higher the level of family support, the lower the level of preoperative anxiety.

PENGEMBANGAN MARKER MULTIEPITOP UNTUK KIT DIAGNOSTIK HPV E6 BERBASIS LATERAL FLOW ASSAY MELALUI PENDEKATAN IN SILICO

Fri, 05 Sep 2025 00:00:00 +0700

Background : Cervical cancer is the second most common cancer after breast cancer and has a high mortality rate from all cancer deaths. Cervical cancer has been proven to be caused by continuous infection of oncogenic types of Human papillomavirus (HPV), namely high-risk HPV types including types 31, 33, 35, and 58. In the HPV life cycle, the E6 protein plays a crucial role in regulating cellular functions that contribute to cell transformation into cancer. The E6 protein from HPV types functions as the main oncoprotein that plays a role in the process of immortalization and cell malignancy. Mechanistically, the E6 protein from high-risk HPV contributes to the inactivation of the p53 tumor suppressor protein. Objective : This study aims to develop a multiepitope marker based on the E6 protein as the main component in the Lateral Flow Assay (LFA. Method : diagnostic kit with a bioinformatics approach method to identify immunogenic and conservative B cell epitopes in the HPV E6 protein which are then cloned in silico in the pET-28a (+) plasmid, so that it can produce a diagnostic kit that is specific for detecting Human papillomavirus (HPV). Result : The results showed that the designed multiepitope marker has the ability to trigger an effective immune response against B cells and has a fairly strong interaction between antigen and antibody. This study also showed the ability of the E6 protein to be expressed on the pET-28a(+) plasmid. Conclusion : This study provides a strong basis for further development and evaluation in vivo studies for the development of lateral flow assay (LFA)-based screening diagnostic kits utilizing Recombinant DNA technology.

UPAYA PENYELESAIAN MASALAH NYERI AKUT PADA GOUT ARTHRITIS MELALUI TINDAKAN PEMBERIAN REBUSAN DAUN SIRSAK (ANNONA MURICATA L)

esa faticha sabiila, Parmilah Parmilah, Tri Suraning Wulandari — Fri, 05 Sep 2025 00:00:00 +0700

Background : Gout arthritis is a metabolic disorder caused by the deposit and accumulation of uric acid in the joints which is characterized by inflammation and stiffness so that it causes pain and pain in the joint area. Gout arthritis pain arises due to the accumulation of monosodium crystals in the veins so that inflammation and swelling occur and then pain occurs. If acute pain is not treated immediately, it will increase the intensity of pain and interfere with daily activities. Non-pharmacological methods such as pain management using a multi-disciplinary approach, namely herbal using soursop leaf decoction.can be used to overcome acute pain problems. Soursop leaves (Annona Muricata L) contain tannin, resin and crytallizable mogostine compounds that are able to overcome joint pain and reduce swelling in gout arthritis sufferers. Objective : to determine the effectiveness of giving soursop leaf decoction to reduce acute pain in gout athritis. Method : case study on 2 female respondents who suffered from gout arthritis with complaints of pain, swelling and heat in the joints. Result : after 7 days of intervention with a frequency of 2 times a day in the morning and evening, there was a decrease in the level of pain from a scale of 6 down to 1-2. Conclusion : the administration of soursop leaf decoction can reduce acute pain in gout arthritis patients.